Beyond Delusions and Dopamine: Negative Symptoms and CIAS - the Forgotten Domains of Schizophrenia

Beyond Delusions and Dopamine: Negative Symptoms and CIAS - the Forgotten Domains of Schizophrenia is organized by Integrity Continuing Education Inc..

Release date: December 22, 2023
Expiration date: December 22, 2024

Description:
Effective treatments for schizophrenia have been available for decades, but by targeting only the dopamine neuropathway, currently available antipsychotics address only the positive symptoms - the voices, delusions, and hallucinations that are the recognizable hallmarks of the disease. However, two other symptom domains - negative and cognitive - can be just as debilitating, yet frequently go unrecognized and untreated. That’s likely because negative symptoms and cognitive impairment associated with schizophrenia (CIAS) are regulated by different, non-dopamine neurotransmitter pathways. Thus far, there have been no treatments to effectively address the flat affect and reduced motivation that are typical of negative symptoms or the poor memory and disorganized thinking that are characteristic of CIAS. Currently, though, several novel therapies are now in development to address these forgotten symptom domains of schizophrenia.
Join schizophrenia experts Dr. Daniel Javitt and Dr. Richard Keefe as they review the signs and traits of CIAS and negative symptoms and outline ways to address these forgotten domains of schizophrenia with current and emerging interventions.

Learning Objectives:
Upon completion of this educational activity, participants should be able to:

• Describe the unmet disease burden of CIAS
• ifferentiate between two underrecognized and undermanaged domains in schizophrenia - negative symptoms and CIAS
• Incorporate an emerging treatment (when available) for patients for CIAS based on clinical trial efficacy, safety, and mechanism of action
• Identify potential benefits and limitations of digital therapeutics in the cognitive and negative and domains