Cancer genomics and transcriptomics Course 2025

Cancer genomics and transcriptomics Course 2025 is organized by European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL - EBI) and will be held from May 12 - 16, 2025.

Description:
This course will focus on the analysis of data from genomic studies of cancer. It will also highlight the application of transcriptomic analysis and single-cell technologies in cancer. Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.

What will I learn?
Learning outcomes:
After the course you should be able to:

• Evaluate the applications and challenges of HTS in the study of cancer genomics
• Detect, visualise, and annotate copy number variation
• Interpret complex genomic rearrangements such as structural variants
• Explain the principles of tumour purity, heterogeneity, and evolution and how we detect or quantify them using bioinformatic approaches
• Explore the application of CRISPR-Cas9 genome editing in cancer studies
• Perform alignment and quantification of expression of RNA-seq datasets
• Explore the application of single-cell sequencing in cancer studies

Course content:
During this course you will learn about:

• Application of high throughput sequencing (HTS) in cancer
• Introduction to cancer genomics and epigenetics
• Structural variation, SNV and CNV analysis, and data visualisation
• Application of CRISPR-Cas9 genome editing in studying cancer
• RNA-seq analysis (both short and long reads)
• Single-cell research in cancer