OVERVIEW

Neuroinflammation and Neurodegeneration is organized by Neuroscience School of Advanced Studies (NSAS) and will be held from Sep 27 - Oct 04, 2025 at Veneto Institute of Sciences, Letters and Arts c/o Palazzo Loredan, Venice, Veneto, Italy.

Description:
It is becoming increasingly clear that neuroimmune mechanisms critically contribute to neurodegeneration. Neuroglial interactions involving microglia and astrocytes govern proper synaptic function, synchronize clearance of toxic aggregates, and coordinate neuroinflammation. Oligodendrocytes and white matter alterations are observed. Furthermore, emerging data raise a crucial role for peripheral-central immune crosstalk in neurodegeneration. How the different non-neuronal cells contribute to neurodegeneration remains, however, elusive. Therapeutic-wise, there is the grand challenge of balancing the positive and negative consequences of these cellular reactions across ageing and brain borders. Thus, deep insight into how various cells work together to resolve neuroinflammation and mediate neuronal health will be necessary to ultimately change the prognosis of neurodegeneration.

The Faculty will bring leading expertise and insight into neuro-glia-immune mechanisms in neurodegeneration. The Advanced Course will delve into the roles of microglia, astrocytes and OPCs in health and pathology and how brain’s various cell types work together to modulate neuronal function and homeostasis in health (development and adult) and distinct disease states.